Polycomb Repressor Proteins in Cancer
Cancer cells are now known to have epigenetic as well as genetic alterations. Polycomb group proteins are involved in chromatin modification and are crucial in many cell fate decisions. Adrian Bracken’s group is investigating whether dysregulation of Polycomb function is involved in tumorigenesis. He is also studying interactions between Polycomb proteins and other transcriptional regulators, in the context of stem cells and differentiation pathways as well as in cancer.
Date: 30 April 2015, 14:30 (Thursday, 1st week, Trinity 2015)
Venue: NDM Building, Headington OX3 7FZ
Speaker: Dr Adrian Bracken (Smurfit Institute of Genetics, Trinity College Dublin)
Organising department: Ludwig Institute for Cancer Research, Oxford Branch
Organiser: Alexandra Ward (University of Oxford, Oxford Ludwig Institute, NDM Experimental Medicine)
Organiser contact email address: alexandra.ward@ludwig.ox.ac.uk
Host: Prof Xin Lu (Ludwig Cancer Research, Oxford Branch)
Part of: Ludwig Institute Seminar Series
Topics: Stem cells, Transcription, Epigenetics, Cancer, Genetics
Booking required?: Not required
Audience: Members of the University only
Editor: Mary Muers