The MAST Proteins in Neurodevelopment and Disease
this talk is CANCELLED!!
Abstract:
The microtubule cytoskeleton plays an indispensable role in building the vertebrate central nervous system. Microtubules mediate the separation of sister chromatids during mitosis, they provide the force to translocate the nucleus in migrating neurons, and they are critical for axon extension as neurons differentiate. This talk focuses on an uncharacterised family of Microtubule Associated Serine Threonine (MAST) Kinases, and how mutations in this gene family cause a spectrum of neurological phenotypes, most notably mega corpus callosum syndrome.The microtubule cytoskeleton plays an indispensable role in building the vertebrate central nervous system. Microtubules mediate the separation of sister chromatids during mitosis, they provide the force to translocate the nucleus in migrating neurons, and they are critical for axon extension as neurons differentiate. This talk focuses on an uncharacterised family of Microtubule Associated Serine Threonine (MAST) Kinases, and how mutations in this gene family cause a spectrum of neurological phenotypes, most notably mega corpus callosum syndrome.
Date:
7 June 2023, 16:00
Venue:
Sherrington Library, off Parks Road OX1 3PT
Speakers:
Speaker to be announced
Organiser:
Cortex Club (University of Oxford)
Organiser contact email address:
demi.brizee@bndu.ox.ac.uk
Part of:
Cortex Club - Oxford Neuroscience Society
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Demi Brizee
