Mapping the Human Body One Cell at a Time
The 37 trillion cells of the human body have a remarkable array of specialised functions, and must cooperate and collaborate in time and space to construct a functioning human. In this talk I will describe my lab’s efforts to understand this cellular diversity through a programme of cell atlasing. Harnessing cutting edge single cell genomics, imaging and computational technologies, we investigate development, homeostasis and disease states, at scale and in 3D, with a particular focus on immunity. I will illustrate the relevance of cell atlas-ing for engineering organoids and regenerative medicine, and will share new results providing insights into pacemaker cells from the sinoatrial node of this heart. Overall I hope to illustrate the power of single cell approaches in unlocking fundamental knowledge about the human body.
Date: 23 February 2022, 16:00 (Wednesday, 6th week, Hilary 2022)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Blakemore Lecture Theatre
Speaker: Dr Sarah A. Teichmann FMedSci FRS (Head of Cellular Genetics, Wellcome Sanger Institute and Director of Research, Cavendish Laboratory, University of Cambridge)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Professor David Paterson (DPAG, University of Oxford)
Organiser contact email address: hod-pa@dpag.ox.ac.uk
Host: Professor David Paterson (DPAG, University of Oxford)
Part of: John Scott Haldane Prize Lecture
Booking required?: Not required
Audience: Members of the University only
Editor: Talitha Smith