OxTalks is Changing
OxTalks will soon be transitioning to Oxford Events (full details are available on the Staff Gateway). A two-week publishing freeze is expected in early Hilary to allow all events to be migrated to the new platform. During this period, you will not be able to submit or edit events on OxTalks. The exact freeze dates will be confirmed as soon as possible.
If you have any questions, please contact halo@digital.ox.ac.uk
Identification of Disease Mechanisms and Potential Therapeutic Targets for ALS and FTD Using Stem Cells
We have used patient-specific stem cell technology to uncover a surprising interplay between gain- and loss-of-function disease mechanisms in the most common form of ALS and FTD, caused by a repeat expansion mutation in C9ORF72. In addition, we have used high-throughput chemical screens on patient-derived neurons to identify novel therapeutic targets for C9ORF72 and sporadic ALS. Recently, we have developed a systematic approach for the identification of gene variants that cause sporadic ALS and are using it to investigate potential new ALS genes with key roles in proteostasis.
Date:
16 April 2018, 11:00
Venue:
Le Gros Clark Building, off South Parks Road OX1 3QX
Venue Details:
Lecture Theatre
Speaker:
Justin Ichida (USC Keck School of Medicine Los Angeles)
Organiser:
Francis Szele (DPAG)
Organiser contact email address:
francis.szele@dpag.ox.ac.uk
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Francis Szele
