Repurposing a drug-target deconvolution technology for enmasse monitoring of protein complex dynamics in intact cells and tissues

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Chris Tan obtained a Bachelor of Science (Molecular Biology) and a Master of Science (Computer Science) from the National University of Singapore. He pursued his doctoral training in Toronto, Canada with the late Prof. Tony Pawson, Prof. Rune Linding and Prof. Gary Bader, making key contributions to our understanding of the evolution of phospho-tyrosine signaling networks (Science, Science Signaling). He is interested in systems biology approaches to address research questions at the boundary of basic science and translational research. Presently, he focuses on applying proteome-wide MS-based approaches to dissect mechanisms of drug action and chemical toxicity, and to understand the molecular basis of gene addiction and drug resistance