Nano- and Microfabricated Hydrogels for Regenerative Engineering
Engineered materials that integrate advances in polymer chemistry, nanotechnology, and biological sciences have the potential to create powerful medical therapies. Our group aims to engineer tissue regenerative therapies using water-containing polymer networks, called hydrogels, that can regulate cell behavior. Specifically, we have developed photocrosslinkable hybrid hydrogels that combine natural biomolecules with nanoparticles to regulate the chemical, biological, mechanical and electrical properties of gels. These functional scaffolds induce the differentiation of stem cells to desired cell types and direct the formation of vascularized heart or bone tissues. Since tissue function is highly dependent on architecture, we have also used microfabrication methods, such as microfluidics, photolithography, bioprinting, and molding, to regulate the architecture of these materials. We have employed these strategies to generate miniaturized tissues. To create tissue complexity, we have also developed directed assembly techniques to compile small tissue modules into larger constructs. It is anticipated that such approaches will lead to the development of next-generation regenerative therapeutics and biomedical devices.
Date: 12 June 2017, 17:00
Venue: Wadham College, Parks Road OX1 3PN
Venue Details: Moser theatre, Wadham College
Speaker: Prof. Ali Khademhosseini (Harvard Medical School)
Organiser contact email address: jae.jung@ouengsoc.org
Booking required?: Recommended
Booking url: https://docs.google.com/forms/d/e/1FAIpQLSfjC9UvRa85Vww1Gvj6CEPEa39pJ77xSPfUqkVjFWmaj6acNQ/viewform?c=0&w=1
Audience: Public
Editor: Sara Saheb Kashaf