CorTalk 8: David Dupret - Rhythms of Memory: from Rodents to Humans
Memory shapes everyday behaviour by engaging complex patterns of neuronal activity distributed across brain networks, including the hippocampus. But what features of neural activity underlie memory-guided behaviour? In this talk, I will explore how spatio-temporally organized spike trains of neuronal ensembles and rhythmic fluctuations in local field potentials contribute to the internal processing of mnemonic information. Drawing on cross-species findings, I will highlight network-level dynamics that support memory across both rodent and human brains. Importantly, I will show how organizational principles and analytical frameworks developed in rodent models are now being leveraged to uncover the oscillatory circuitry underlying human memory. These insights reveal how fine-grained neural dynamics, distributed across the hippocampus and its partner circuits, orchestrate memory-guided behaviour in the mammalian brain.
Date: 5 December 2025, 16:00
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Event to take place in the Blakemore Lecture Theatre
Speaker: Dr David Dupret (MRC Brain Network Dynamics Unit, Department of Pharmacology, University of Oxford)
Organiser: Luba Samson (University of Oxford)
Organiser contact email address: liubou.samson@lmh.ox.ac.uk
Host: Cortex Club (University of Oxford)
Booking required?: Not required
Cost: No cost
Audience: Public
Editor: Garry Cherepakhov