Investigating the mechanisms of regulatory T-cell differentiation in vivo by novel Fluorescent Timer reporters
Dr Masahiro Ono was originally trained as a dermatologist, and later specialised in molecular and systems immunology. He obtained his PhD in 2006 on autoimmunity and regulatory T cells, and thereafter, worked on the molecular mechanism of the transcription factor Foxp3, revealing the interaction of Foxp3 and the transcription factor Runx1 and their transcriptional mechanisms. In 2009, he obtained a Human Frontier Science Program Long-Term Fellowship, and joined University College London (UCL). Thus he extended his expertise to genomics and systems analysis, establishing a new multidimensional framework for visualising transcriptomic data and unravelling complex processes in T cell differentiation. In 2012, he was awarded a prestigious Biotechnology and Biological Sciences Research Council (BBSRC) David Phillips Fellowship, thereby established his lab in UCL. In 2015, he was appointed to a proleptic Senior Lecturer in the Department of Life Sciences, Imperial. He is conducting multidisciplinary projects on the transcriptional programme of T cell memory and immune regulation.
Date: 9 October 2017, 12:00
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: Bernard Sunley Lecture Theatre
Speaker: Dr Masahiro Ono, MD, PhD (Imperial College London)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers: Professor Irina Udalova (Kennedy Institute of Rheumatology), Jo Silva (NDORMS), Wulf Forrester-Barker (University of Oxford, Nuffield Dept of Orthopaedics Rheumatology and Musculoskeletal Sciences), Laura Hume (Kennedy Institute of Rheumatology)
Host: Professor Fiona Powrie (Kennedy Institute of Rheumatology)
Part of: Kennedy Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Laura Sanchez Lazo