From Models to Mechanisms: Targeting BBB Dysfunction in Neurodegeneration Models
Dr Mootaz Salman (University of Oxford) will explore how innovative organoid and 3-D brain models are advancing our understanding of blood–brain barrier dysfunction in neurodegenerative diseases. By integrating cellular neuroscience, bioengineering, and disease modelling, his work reveals how inflammation- and mechanically-driven changes contribute to barrier breakdown and neuronal decline. This research offers new insights into the mechanisms of neurodegeneration and highlights emerging therapeutic strategies to restore brain health.
Date: 12 November 2025, 16:00
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: event will take place in the Blakemore Lecture Theatre
Speaker: Dr Mootaz Salman (DPAG, University of Oxford)
Organisers: Ivan Peckar (University of Oxford), Luba Samson (University of Oxford)
Organiser contact email address: liubou.samson@lmh.ox.ac.uk
Host: Cortex Club (University of Oxford)
Booking required?: Not required
Audience: Public
Editor: Garry Cherepakhov