Dendritic spine dynamics underlying animal behaviours
Dendritic spines are the major memory elements in the brain, and their properties deeply influence brain functions and disorders. I will introduce recent findings in our laboratory: GABA actions on spine shrinkage and elimination, a critical time window for dopamine on spine enlargement for reinforcement learning, intrinsic turnovers of spines in wild type and fragile X mice, spine enlargement in neocortical pyramidal neurons of awake adult mice, and protein-synthesis dependent optogenetic probes to image and manipulate memory spines and animal behaviors.
Date: 23 March 2015, 16:00 (Monday, 10th week, Hilary 2015)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Library
Speaker: Dr Haruo Kasai (The University of Tokyo)
Organisers: Michael Song (University of Oxford), Sebastian Vasquez Lopez (University of Oxford), Oliver Barnstedt (University of Oxford)
Organiser contact email address: oliver.barnstedt@cncb.ox.ac.uk
Host: Sebastian Vasquez Lopez (University of Oxford)
Part of: Cortex Club
Topics:
Booking required?: Not required
Booking url: http://www.cortexclub.com/
Audience: Public
Editor: Oliver Barnstedt