Pulse trains to percepts: The challenge of creating a perceptually intelligible world with sight recovery technologies

Retinal diseases affect more than 20 million individuals worldwide. An extraordinary variety of sight recovery therapies are either about to begin clinical trials, have begun clinical trials, or are currently being implanted in patients. However, as yet we have little insight into the perceptual experience likely to be produced by these implants – what will the world look like to patients? I will discuss the interplay between the various kinds of sight recovery procedures and the underlying biology of the retina and cortex, and create neuro-perceptual models to create movies simulating what people with ‘restored vision’ are likely to ‘see’.