The Quest for Neuroprotection in Parkinson’s disease: reversing synaptic dysfunction
Please note this talk is at noon in the small lecture theatre
Austen Milnerwood’s research centers on cell biological, electrophysiological and optical investigation of neural development, connectivity, transmission and plasticity. With a major focus on the early pathophysiology of adult-onset diseases such as movement disorders and dementia, his laboratory aims to develop neuroprotective treatments.

A strong theme has emerged from studying several proteins harbouring mutations that are autosomal dominantly linked to Parkinson’s disease, in other words, genes transmitted down the family line that are highly predictive for developing PD. There are several proteins that cause “familial PD,” e.g. LRRK2, VPS35 and synuclein. Milnerwood’s laboratory is finding that these proteins are involved in the same cellular functions. By learning more about what these proteins are supposed to do and what goes wrong with the mutations present, Milnerwood hopes to work out the common neuronal dysfunction of many forms of parkinsonism and then develop appropriate treatments.
Date: 11 July 2019, 12:00 (Thursday, 11th week, Trinity 2019)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Small Lecture Theatre (2nd Floor)
Speaker: Austen Milnerwood (McGill University)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Melanie Witt (University of Oxford, Department of Earth Sciences, Department of Physiology Anatomy and Genetics)
Organiser contact email address:
Part of: OPDC Seminar Series (DPAG)
Booking required?: Not required
Audience: Members of the University only
Editors: Melanie Witt, Talitha Smith