A probiotic turn is underway in various domains of health and environmental management. Probiotic approaches introduce organisms into ecological systems and manage their dynamics to restore desired functions and services. They aim to address the problems caused by the overreach of modern, antibiotic approaches that have simplified and degraded ecological systems and compromised their resilience and sustainability. This talk provides an overview of this shift, and illustrates its implications for agriculture and food. It focuses on the example of regenerative agriculture and the roles it affords livestock, plants and microbes in tackling environmental problems.