Tissue T cells: Life in Lockdown in Liver and Lung
In person only
My lab focuses on human tissue-resident T cells and their interactions in order to harness them for novel immunotherapeutic approaches, in particular pan-coronavirus prophylactic vaccines and therapeutic vaccines for hepatitis B and hepatocellular carcinoma. I will discuss our recent work on stromal-mediated instruction of liver-resident T cells by myeloid cells (Pallett et al, Nature 2023). I will also show data on liver-resident NK cell regulation of hepatitis B-specific T cells and immunotherapeutic strategies to overcome this (Diniz et al, Sci Trans Med 2023 and unpublished).
Date: 4 March 2024, 12:00 (Monday, 8th week, Hilary 2024)
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: Lecture Theatre
Speaker: Prof Mala Maini (UCL Institute of Immunity and Transplantation)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organiser: Doris Chan (Kennedy Institute of Rheumatology)
Organiser contact email address: doris.chan@kennedy.ox.ac.uk
Host: Dr Jelena Bezbradica (The Kennedy Institute of Rheumatology)
Part of: Kennedy Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Doris Chan