9:00 – 9:30 REGISTRATION, TEA & COFFEE
9:30 – 9:45 OPENING REMARKS
Professor Kevin Talbot and Professor Tom Gillingwater
9:45 – 10:30 KEYNOTE LECTURE:
SMN-BASED THERAPIES IN THE POST-NUSINERSEN ERA
Professor Volker Straub
10:30 – 10:50 UBIQUITIN PATHWAYS IN SMA
Professor Tom Gillingwater
10:50 – 11:10 STEM CELL MODELS
Professor Kevin Talbot
11:10 – 11:40 REFRESHMENTS
11:40 – 12:00 ZEBRAFISH AS A TOOL FOR DRUG DISCOVERY
Professor Catherina Becker
12:00 – 12:20 PTEN IN SMA
Dr Ke Ning
12:20 – 12:40 OPTIMISING SMA GENE THERAPY: OF VECTORS, ROUTES AND
BARRIERS
Dr Rafael Yáñez
12:40 – 13:00 THE GLUCOCORTICOID-KLF15-BCAA PATHWAY AS A NOVEL
THERAPEUTIC PATHWAY FOR SMA
Dr Melissa Bowerman
13:00 – 14:20 LUNCH
UK SMA Research Meeting
13th June 2017
14:20 – 14:40 TITLE TBA
Professor Mimoun Azzouz
14:40 – 15:00 TITLE TBA
Professor Simon Parson
15:00 – 15:20 THE APPLICATION OF MICRORNA AS A BIOMARKER IN SPINAL
MUSCULAR ATROPHY
Dr Haiyan Zhou
15:20 – 15:50 REFRESHMENTS
15:50 – 16:10 CELLULAR AND MOLECULAR MECHANISMS INVOLVED IN
MOTOR NEURONE DEGENERATION AND VULNERABILITY
Dr Alison Thomson
16:10 – 16:30 AN INTEGRATIVE-OMICS APPROACH FOR THE IDENTIFICATION
OF THERAPEUTIC TARGETS FOR SMA
Dr Heidi Fuller
16:30 – 16:50 OUTCOME MEASURES FOR SMA: A DEVELOPING FIELD
Dr Mariacristina Scoto
16:50 – 17:00 CLOSING REMARKS
Professor Matthew Wood