OxTalks is Changing
OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The History and Philosophy of Placebo Treatments in Clinical Practice and Clinical Trials
Drawing from his seminal work The Power of Placebos (Johns Hopkins University Press), Professor Jeremy Howick presents a rigorous examination of placebo and nocebo phenomena that challenges fundamental assumptions in contemporary medical research and clinical practice. This keynote advances the argument for a paradigm shift beyond the first placebo revolution, which established scientific legitimacy for placebo effects, toward a more ethically grounded and methodologically sophisticated approach to therapeutic intervention.
The presentation critically interrogates the widespread deployment of placebo controls in clinical trial design, systematically deconstructing the purported methodological advantages including assay sensitivity, absolute effect size determination, and participant recruitment efficiency. Professor Howick demonstrates that these justifications lack robust scientific foundation when proven therapeutic alternatives exist, raising profound ethical concerns about withholding established treatments from research participants.
Central to this discourse is the imperative to harness placebo mechanisms through evidence-based clinical communication, therapeutic alliance building, and contextual healing factors. The keynote explores how negative expectancy effects—nocebo phenomena—can undermine treatment efficacy through iatrogenic harm, while positive therapeutic contexts can enhance clinical outcomes through neurobiologically mediated pathways.
This scholarly presentation advocates for methodological reform in clinical research ethics, proposing restrictions on placebo-controlled trials when proven therapies are available, while simultaneously calling for the systematic integration of placebo science into evidence-based medical practice.
Date:
13 October 2025, 17:15
Venue:
Rewley House, 1-7 Wellington Square OX1 2JA
Venue Details:
Lecture Theatre
Speaker:
Professor Jeremy Howick (University of Leicester)
Organising department:
Department for Continuing Education
Organiser:
Ashleigh Denton
Organiser contact email address:
cpdhealth@conted.ox.ac.uk
Booking required?:
Required
Booking url:
https://lifelong-learning.ox.ac.uk/events/view/the-history-and-philosophy-of-placebo-treatments-in-clinical-practice-and-clinic
Cost:
Free
Audience:
Public
Editor:
Ashleigh Denton
