CHG Lunchtime Lab Talks: Carroll Group


There is no need to register. If you are not a member of the Centre for Human Genetics and are attending in person, you will need to show your University card at reception, and sign in and out of the building.

The Lunchtime Lab Talks aim to introduce and highlight the broad spectrum of research that is carried out at the Centre and encourage multidisciplinary interactions. Throughout the year, groups are invited to speak and present their work to our community.

Lunch is available from 12:15 in Room A&B and talks run from 12:30–13:30.

Carroll Group
Speaker: Jakub Hantabal
Title: ‘Characterising the host-pathogen interactions of henipaviruses.’
Abstract: Nipah virus (NiV) is a highly virulent emerging pathogen that causes severe respiratory disease and encephalitis, with no effective vaccines or treatments. Although the clinical progression is known, a limited understanding of host-virus interactions hampers therapeutic development. This project addresses that gap by studying henipaviral infections using in vitro and in vivo models. Specifically, we investigate NiV’s neurological tropism using iPSC-derived brain organoids to explore its impact on various nervous system cells, and we examine immune responses in infected brain and lung tissues using the CellDIVE multiplex immunofluorescence platform on Syrian hamster models. Our studies provide novel insights into NiV’s neurological targeting and immune cell infiltration during infection.