On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
MHC class I-peptide complexes are usually stable for hours or even days. We have found that small molecules – for example certain dipeptides – that bind into the F pocket can dramatically accelerate peptide dissociation and replacement with exogenous peptides. This works on recombinant class I molecules, where the technology can be used to rapidly manufacture MHC multimers for T cell staining, and on cell surfaces, from which peptides can now be natively eluted.
