Oxford Events, the new replacement for OxTalks, will launch on 16th March. From now until the launch of Oxford Events, new events cannot be published or edited on OxTalks while all existing records are migrated to the new platform. The existing OxTalks site will remain available to view during this period.
From 16th, Oxford Events will launch on a new website: events.ox.ac.uk, and event submissions will resume. You will need a Halo login to submit events. Full details are available on the Staff Gateway.
MHC class I-peptide complexes are usually stable for hours or even days. We have found that small molecules – for example certain dipeptides – that bind into the F pocket can dramatically accelerate peptide dissociation and replacement with exogenous peptides. This works on recombinant class I molecules, where the technology can be used to rapidly manufacture MHC multimers for T cell staining, and on cell surfaces, from which peptides can now be natively eluted.