OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Rachael will discuss approaches to combining multi-omics and imaging approaches to probe the adaptive immune responses in health and disease. Her talk will span approaches to monitor haematological malignancies and understanding clonal heterogeneity, to using single cell transcriptomics coupled with immune cell receptor (BCR and TCR) sequencing and CITE-seq to decipher the nature of immune cells in tumour microenvironment. She will discuss some recent approaches for achieving data quality, as well as going from omics to mechanism.
_________________________________________
Rachael did her PhD at Wellcome Sanger Institute where she developed methods for B and T cell receptor sequencing for characterising adaptive immune responses in health, leukaemia and infectious disease. Then she went onto win the Sir Henry Wellcome Fellowship in University of Cambridge working on characterising B cell dysfunction in autoimmune diseases and the effects of different immunomodulatory therapies. Now she is a group leader at the Wellcome Centre of Human Genetics at the University of Oxford. Her lab is developing and exploiting novel experimental and computational methods to decipher the mechanistic basis of immune cell regulation across immunological diseases and cancers from novel perspectives to hopefully provide insights for guiding better therapeutics.