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Inherited arrhythmias: from bench to bedside and back
Dr Priori, is Professor of Cardiology in the Department of Molecular Medicine at the University of Pavia. She is a world leader in the field of inherited arrhythmias and cardiomyopathies. She combines clinical work with basic research and, among other important achievements, she discovered the gene that causes the autosomal dominant form of Catecholaminergic Polymorphic Ventricular Tachycardia and developed the first animal model that allowed the understanding of the mechanisms for arrhythmogenesis. Based on this discovery she demonstrated the antiarrhythmic activity of Inhibition of CAMKII that is now advancing toward the development of a drug for humans and she demonstrated in the mouse model of the disease the efficacy of an RNA interference strategy to correct the consequences of the molecular defect (gene therapy).
Date:
8 October 2018, 17:00
Venue:
Sherrington Building, off Parks Road OX1 3PT
Venue Details:
Large Lecture Theatre
Speaker:
Professor Silvia G. Priori (University of Pavia, Italy)
Organising department:
Department of Physiology, Anatomy and Genetics (DPAG)
Host:
Professor Manuela Zaccolo MD (DPAG, University of Oxford)
Part of:
Burdon Sanderson Prize Lecture
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Isabella Renehan
