OxTalks is Changing
OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Targeting HLA-E and NKG2A in solid tumors to overcome resistance to cancer immunotherapies
Dr. Horowitz’s research focuses on human Natural Killer (NK) cells and CD8 T cells and their functional roles in microbial infections and cancer, autoimmunity, pregnancy and in transplantation. His analyses are designed to identify specific subsets of NK and CD8 T cells with enhanced immunotherapeutic (or pathogenic) potential, as well as to identify pathways regulating NK cell function that can be perturbed for therapeutic benefit. To achieve this goal, Dr. Horowitz’s lab uses an array of cutting-edge technologies, including mass cytometry (CyTOF), multiplexed in situ imaging, Olink proteomics, and single-cell and Spatial RNA sequencing along with genomic data on HLA class I and KIR genes to profile NK and CD8 T cells with ultra-resolution. His lab has established relationships with surgical and medical oncologists to create a translational framework for exploiting NK cells to improve T cell targeted therapies. In his presentation, Dr. Horowitz will discuss his current research in human bladder and non-small-cell lung cancers
Date:
3 October 2025, 13:00
Venue:
NDMRB Seminar Room, NDM Research Building, Old Road Campus, Roosevelt Drive, Headington, OX3 7BN
Speaker:
Dr. Amir Horowitz (Assistant Professor of Oncological Sciences, Icahn School of Medicine, Mount Sinai)
Organising department:
Nuffield Department of Clinical Medicine
Organiser:
Karen Poxon (University of Oxford)
Organiser contact email address:
karen.poxon@ndm.ox.ac.uk
Host:
Dr. Malcolm Sim (University of Oxford, Centre for Immuno-oncology)
Part of:
CIO Seminar Series
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Karen Poxon
