The Invasive Respiratory Infection Surveillance (IRIS) Consortium is a consortium of over 100 investigators working in over 50 microbiology reference laboratories in 30 countries worldwide. IRIS was established at the start of the pandemic and has been tracking changes in life-threatening invasive bacterial diseases like meningitis, septicaemia and pneumonia during the pandemic and also now post-pandemic. Professor Brueggeman will be presenting the recent findings of the Consortium.