Cell type-specific translation profiling in fragile X
Chancellor’s Fellow, Centre for Integrative Physiology, University of Edinburgh
Dr Osterweil’s research questions are being investigated in multiple neural circuits using biochemical, electrophysiological and systems-level approaches.

Current projects include:
Determining the role of NMDA receptors in local protein synthesis
Tracking cell type specific changes in translation during plasticity using cell type-specific Translating Ribosome Affinity Purification and RNA-seq
Investigating the translation control pathways linked to different postsynaptic receptors
Exploring the role of protein turnover in synaptic plasticity​

Dr Osterweil’s group are studying these basic biological questions using animal models of fragile X syndrome, Tuberous Sclerosis, and other neurodevelopmental disorders. It is their belief that identifying the mechanisms that go awry in these models will simultaneously address fundamental questions of synaptic function, and provide a better understanding of autism and ID.
Date: 23 January 2018, 12:00 (Tuesday, 2nd week, Hilary 2018)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Small Lecture Theatre - 2nd floor
Speaker: Dr Emily Osterweil (University of Edinburgh)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Melanie Witt (University of Oxford, Department of Earth Sciences, Department of Physiology Anatomy and Genetics)
Organiser contact email address: opdc.administrator@dpag.ox.ac.uk
Part of: OPDC Seminar Series (DPAG)
Booking required?: Not required
Audience: Members of the University only
Editor: Melanie Witt