On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
CD8+ T cells can recognise and kill virus-infected cells and cancer cells. Understanding how they first recognise antigen, then proliferate and differentiate, is crucial to improving the design of vaccines and immunotherapy for viral infections and cancer. The immunology canon teaches us that a subset of dendritic cells (CLEC9A+ XCR1+ “DC1”) initiates CD8+ T cell responses in lymph nodes. However single cell and spatial data from human lymphoid tissue suggest DC1 are unlikely to fulfil this role in humans. What are the alternative scenarios for “priming” human CD8+ T cells – and what are the implications for immune therapy?
