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OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
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Epigenetic technologies to advance cancer detection and cancer biology
My laboratory is interested in understanding the chemical modifications of our genome, transcriptome, and proteome in human health and disease – cancer in particular – and translating this information into diagnostic and therapeutic opportunities that ultimately benefit patients. To do so, we use our unique expertise in chemical biology to develop cutting-edge technologies to decode the wealth of epigenetic information. Most notably, we developed TAPS, a revolutionary bisulfite-free and base-resolution direct sequencing method for DNA epigenetic modifications. We have further demonstrated the application of TAPS in cell-free DNA for accurate identification of early liver cancer and pancreatic cancer. Our ongoing efforts aim to establish a comprehensive human epigenetic tissue atlas, as well as develop single-cell epigenetic sequencing to study tumour heterogeneity. We are also developing novel RNA modification sequencing methods to decipher the epitranscriptome in cancer.
Date:
19 September 2023, 9:30
Venue:
Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details:
Room A&B
Speaker:
Dr Chunxiao Song (Ludwig Institute for Cancer Research, University of Oxford)
Organiser:
Dr Ricardo Fernandes (CAMS Oxford Institute, University of Oxford)
Organiser contact email address:
coi.admin@ndm.ox.ac.uk
Part of:
CAMS Oxford Institute Seminars
Booking required?:
Not required
Booking url:
https://us02web.zoom.us/j/85069685687
Cost:
free
Audience:
Members of the University only
Editor:
Natalie Baker