OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
We develop a novel method DeMixT for the gene expression deconvolution of three compartments in cancer patient samples: tumor, immune and surrounding stromal cells. In validation studies using mixed cell line and laser-capture microdissection data, DeMixT yielded accurate estimates for both cell proportions and compartment-specific expression profiles. Application to the head and neck cancer data shows DeMixT-based deconvolution provides an important step to link tumor transcriptome data with clinical outcomes.
