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Building a flexible sensory cortex: Function and dysfunction
Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
Animals adapt their behaviour in response to variable changes in reward reinforcement. The prefrontal areas of the mammalian neocortex, especially the orbitofrontal cortex (OFC), play an important role in invoking rule-based strategies to enable flexible learning. However, the neural circuit mechanisms in OFC and its hierarchical interactions with sensory areas underlying such processes remain elusive. In my talk, using a tactile reversal-learning task in mice, I will discuss cellular and circuit interactions between orbitofrontal and somatosensory cortices that guide flexible tactile decision-making. I will also present data on how flexible behaviour and feedback regulation of sensory processing is disrupted in animal models of autism spectrum disorders.
Date:
7 March 2023, 12:00
Venue:
Pharmacology, off Mansfield Road OX1 3QT
Venue Details:
David Smith Lecture Theatre
Speaker:
Dr Abhishek Banerjee (Newcastle University)
Organising department:
Department of Pharmacology
Organiser:
Carolyn Thackrah (University of Oxford, Department of Pharmacology)
Organiser contact email address:
carolyn.thackrah@pharm.ox.ac.uk
Host:
Dr Tim Viney (Department of Pharmacology, University of Oxford)
Part of:
Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Carolyn Thackrah
