At the intersection of ER protein quality control and lipid droplets

The Olzmann research group aims to improve understanding of protein and lipid homeostasis in health and disease. Although dysregulation of lipid droplet functions is central to the etiology of metabolic diseases, very little is known regarding the mechanisms that control lipid droplet biogenesis and function. The Olzmann group is applying advanced technological platforms to achieve a comprehensive and mechanistic understanding how lipid droplets are formed and regulated to maintain health.