Understanding the molecular logic of Adhesion GPCRs in mechanosensation
Anyone interested in meeting with Tobi should please contact maike.glitsch@dpag.ox.ac.uk
G protein coupled receptors (GPCR) have proven a treasure trove for modern pharmacological intervention of numerous human ailments. However, in stark contrast to classically targeted GPCRs, adhesion GPCRs habe been largely neglected by biologists, pharmacologists and clinician scientists for decades. Only recently their physiological and signaling properties are being unravelled and show exciting features including their roles in tissue architecture, signaling through tethered agonism and their unusual activation through mechanical cues. This seminar will discuss the recent developments on adhesion GPCR signaling and introduce the receptor family as a topical area in neuroscience and cancer research.
Date: 19 June 2018, 12:00 (Tuesday, 9th week, Trinity 2018)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Sherrington Room
Speaker: Tobias Langenhan (Leipzig University)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Isabella Renehan (Department of Physiology Anatomy and Genetics)
Host: Professor Maike Glitsch (DPAG, University of Oxford)
Part of: Cell Physiology Theme Guest Speakers (DPAG)
Booking required?: Not required
Audience: Members of the University only
Editor: Isabella Renehan