Inauguration Talk: "Structural Mechanisms of Macromolecular Assemblies: from HIV-1 Capsid to Bacterial Chemosensory Arrays"
Structural Biology using single particle cryoEM and molecular/cellular cryo-electron tomography (cryoET) has become a major tool for studying macromolecular assemblies that are intrinsically flexible and dynamic, and often function in higher-order assemblies that are difficult to purify. The study of these complexes in situ using cryoET and sub-tomogram averaging at near atomic resolution, coupled with cryoFIB and correlative/integrative imaging, opens a new frontier in structural cell biology, as exemplified in virus infection and bacterial chemotaxis signaling.
Date: 16 May 2018, 15:45
Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details: Meeting rooms A & B
Speaker: Prof Peijun Zhang (University of Oxford)
Organising department: Wellcome Trust Centre for Human Genetics
Organiser: Agata Krupa (Wellcome Trust Centre for Human Genetics)
Hosts: Prof Yvonne Jones (University of Oxford), Prof David Stuart (University of Oxford)
Part of: Strubi seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Agata Krupa