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How do we discover new antibiotics?
Antimicrobial resistance is an urgent threat to human health, with the rise in resistant bacteria coupled with a decline in the development of new antibiotics. This talk will present an overview of approaches to discovering both new antibiotics and non-traditional antimicrobial agents. Research projects from our group will be used to illustrate some of these tactics, including a crowdsourcing initiative designed to uncover novel chemical diversity with antimicrobial activity (the Community for Open Antimicrobial Drug Discovery), a ‘rediscovery’ approach focused on a neglected antibiotic initially identified over 50 years ago, and novel approaches based on adding additional functionality to existing antibiotics. Without significant changes in treating drug-resistant infections, we face a return to a pre-antibiotic era where a simple scratch can kill.
Date:
29 September 2025, 14:00
Venue:
Dorothy Crowfoot Hodgkin Building, off South Parks Road OX1 3QU
Venue Details:
seminar room 20-138
Speakers:
Speaker to be announced
Organising department:
Department of Biochemistry
Organiser:
Stephan Uphoff (University of Oxford)
Organiser contact email address:
stephan.uphoff@bioch.ox.ac
Host:
Stephan Uphoff (University of Oxford)
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Stephan Uphoff
