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Peter Cresswell is an immunologist whose research focuses on specific processing mechanisms that play a role in the antigen processing system. He is also interested in the mechanisms by which interferons eliminate viral infection during the innate immune response, our first line of defence against invading pathogens.
Peter and his team focus on the functions of major histocompatibility complex (MHC) and CD1, which bind peptides from foreign antigens and lipids, respectively. This binding process creates complexes that are recognised by the immune system and subsequently marked for removal by T cells from the body.
Peter cloned the TAP-associated glycoprotein, known as tapasin, which is essential for effective generation of MHC class I peptide complexes, and viperin — a critical component of the interferon-induced response to viral infection. contributions, He is a member of the US National Academy of Sciences, the American Academy of Arts and Sciences, the Institute of Medicine and is a Fellow of the Royal Society.
