OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Infectious disease-causing pathogens have plagued humanity since antiquity, and the COVID-19 pandemic has been a vivid reminder of this perpetual existential threat. Vaccination has saved more lives than any other medical procedure, and effective vaccines have helped control the COVID-19 pandemic. However, we do not have effective vaccines against rapidly mutating viruses, such as HIV; nor do we have a universal vaccine against seasonal variants of influenza or SARS-CoV-2 variants that may evolve in the future. The ability to develop effective vaccines that protect us from highly mutable viruses will help create a more pandemic-resilient world. I will describe how by bringing together approaches from statistical physics, virology and immunology, progress is being made to address this challenge. I will focus on broadly protective antibody responses. First, I will describe some general principles and then I will discuss how by combining physics-based modeling and data from humans who received COVID vaccines we are learning new mechanisms underlying the antibody response upon infection or vaccination.