Spreading mechanics and differentiation of astrocytes during retinal development
In embryonic development, formation of the retinal vasculature is critically dependent on prior establishment of a mesh of astrocytes.
Astrocytes emerge from the optic nerve head and then migrate over the retinal surface in a radially symmetric manner and mature through
differentiation. We develop a PDE model describing the migration and differentiation of astrocytes, and numerical simulations are compared to
experimental data to assist in elucidating the mechanisms responsible for the distribution of astrocytes via parameter analysis. This is joint
work with Timothy Secomb.
Date:
29 April 2022, 14:00 (Friday, 1st week, Trinity 2022)
Venue:
Mathematical Institute, Woodstock Road OX2 6GG
Venue Details:
Virtual
Speaker:
Prof Tracy Stepien (University of Florida)
Organising department:
Mathematical Institute
Organiser:
Sara Jolliffe (University of Oxford)
Organiser contact email address:
sara.jolliffe@maths.ox.ac.uk
Host:
Dr Ruth Baker (University of Oxford)
Part of:
Mathematical Biology and Ecology
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Sara Jolliffe
