Pathway to Parkinson’s Disease: A Tale of Two Genes
The Moore Laboratory investigates the molecular pathophysiology of Parkinson’s. The majority of Parkinson’s cases occur in a sporadic manner although 5 to 10 percent of cases are inherited, with causative mutations identified in at least eight genes. The Moore Laboratory studies the normal biology and pathobiology of gene products that cause inherited Parkinson’s, including the common leucine-rich repeat kinase 2 (LRRK2, PARK8), the retromer component VPS35 (PARK17), the E3 ubiquitin ligase parkin (PARK2), and the lysosomal P5-type ATPase ATP13A2 (PARK9).
Date: 16 April 2019, 16:00 (Tuesday, -1st week, Trinity 2019)
Venue: Sherrington Library, off Parks Road OX1 3PT
Speaker: Darren Moore (Van Andel Research Institute)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Melanie Witt (University of Oxford, Department of Earth Sciences, Department of Physiology Anatomy and Genetics)
Organiser contact email address: opdc.administrator@dpag.ox.ac.uk
Part of: OPDC Seminar Series (DPAG)
Topics: Parkinson's disease
Booking required?: Not required
Audience: Members of the University only
Editor: Melanie Witt