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Engineering T Cell Recognition: From Antigen Discovery to Programmable Immunotherapy
Places are limited, and registration is required. Please register in advance.
Effective cancer immunotherapy requires identifying tumor-associated antigens and engineering T cells to recognize them precisely. I will discuss our recent development of complementary technologies: HLA-Shuttle, which reveals hidden antigens in immune-cold tumors; HLA3DB, a database of peptide conformational features; and TRACeR-I, a protein engineering platform for developing antigen-specific binding modules with programmable HLA restriction. Together, these tools address key bottlenecks in the antigen discovery-to-therapy pipeline
Date:
2 March 2026, 13:00
Venue:
Zoom, registration is required
Speaker:
Nikolaos Sqourakis (University of Pennsylvania)
Organising department:
MRC Weatherall Institute of Molecular Medicine
Organisers:
Hashem Koohy (University of Oxford),
WIMM Academics
Organiser contact email address:
hashem.koohy@rdm.ox.ac.uk
Part of:
Unravelling T Cell Recognition: Insights from immunology and AI
Booking required?:
Required
Booking url:
https://bit.ly/3O7u9PG
Cost:
0
Audience:
Public
Editor:
Hashem Koohy
