Adapting protein quality control for intervention in neurodegenerative diseases (CANCELLED)
Unfortunately due to unforseen circumstances, this seminar has had to be cancelled
Protein folding is tightly regulated by molecular chaperones and other protein quality control mechanisms such as the ubiquitin proteasome system and autophagy to ensure the integrity of the proteome. However, these systems can fail to prevent protein misfolding, leading to protein aggregation and amyloidosis. They are underlying reasons for many neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease or Huntington’s disease. Interfering with protein quality control systems and modulating posttranslational modifications of proteins in neuronal cells can reduce aggregation and ameliorate amyloidosis.
Date:
6 June 2018, 12:00 (Wednesday, 7th week, Trinity 2018)
Venue:
Medawar Building, off South Parks Road OX1 3SY
Venue Details:
Level 30 Seminar Room
Speaker:
Heidi Olzscha (University of Oxford)
Organising department:
Nuffield Department of Clinical Medicine
Organisers:
Dr Proochista Ariana (University of Oxford),
Professor Sunetra Gupta (University of Oxford),
Prof Lynn Dustin (NDORMS)
Organiser contact email address:
thomas.johnson@tss.ox.ac.uk
Host:
Professor Sunetra Gupta (University of Oxford)
Part of:
Peter Medawar Building Seminars
Topics:
Booking required?:
Not required
Cost:
FREE
Audience:
The scientific communnity
Editor:
Thomas Johnson
