Next generation brain maps – concepts, challenges, collaboration
The human brain is a highly complex system, with different levels of spatial organisation. E.g., on a macroscopic level, the brain shows a highly variable folding pattern, while nerve cells on a microscopical level are arranged in layers and columns in a regionally specific way. Cytoarchitecture is a concept that itself encompasses different aspects of brain organization – the different cell types have distinct morphology, molecular, genetic and connectional fingerprints. Axons form complex networks at the level of microcircuits or large cognitive system. To capture the cellular and axonal architecture and to study the role of a specific brain region to function or behaviour requires to analyse the brain in 3D with microscopical resolution. Deep-learning offers new tools to 3D reconstruct images of histological sections at the microscopical scale, and convolutional neuronal networks support to automatize brain mapping. Considering the size of the brain with its nearly 86 billion nerve cells, HPC-based workflows play an increasing role for developing high-resolution brain models, to tame brain complexity. To develop such tools is key in the Human Brain Project. It is building a European research infrastructure for brain research, to collaborate towards a better understanding of the human brain.
Date:
17 May 2019, 13:00 (Friday, 3rd week, Trinity 2019)
Venue:
Sherrington Building, off Parks Road OX1 3PT
Venue Details:
Large Lecture Theatre
Speaker:
Prof. Dr. Med. Katrin Amunts (Institute of Neuroscience and Medicine Structural & Functional Organization of the Brain (INM-1), Jülich C. & O. Vogt Institute of Brain Research)
Organising department:
Department of Physiology, Anatomy and Genetics (DPAG)
Organiser:
Professor Kristine Krug (DPAG, University of Oxford)
Organiser contact email address:
hod-pa@dpag.ox.ac.uk
Host:
Professor Kristine Krug (DPAG, University of Oxford)
Part of:
DPAG Head of Department Seminar Series
Topics:
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Talitha Smith
