Understanding the pathways underlying residual visual function after damage to primary visual cortex
Damage to the primary visual cortex leads to loss of the visual field contralateral to the damaged cortex. However, in spite of this loss, some patients are still able to detect visual information about stimuli presented within their blind field. A growing area of research aims to exploit this residual visual function to try to improve visual performance through rehabilitation programmes stimulating the blind field. However, to optimise such programmes it is important to understand the pathways through which this information is conveyed.

Here I will present a series of magnetic resonance imaging studies in which we attempted to elucidate these pathways in a group of hemianopic patients. Firstly I will explain how our functional MRI studies use the specific pattern of response to visual stimulation in different visual areas to uncover candidate pathways. I will use diffusion-weighted data to provide support for a pathway between the lateral geniculate nucleus and motion area MT that is consistently intact only in patients showing blindsight abilities. Finally, I will present our most recent data in which we find further support for this pathway using functional connectivity analysis.
Date: 1 February 2019, 13:00 (Friday, 3rd week, Hilary 2019)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Large Lecture Theatre
Speaker: Associate Professor Holly Bridge (NDCN, University of Oxford)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Host: Professor Kristine Krug (DPAG, University of Oxford)
Part of: DPAG Head of Department Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Talitha Smith