On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
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The ability to sense and respond to danger appropriately is critical for maintaining immune homeostasis. Inflammasomes are supra-molecular protein complexes that sense danger signals both from microbes and tissue damage, and initiate an inflammatory response through activation of the protease caspase-1 and subsequent release of interleukin(IL)-1β and IL-18. Dysregulation of inflammasomes contributes to the progression of chronic disease such as Alzheimer’s disease, COPD, or Rheumatoid Arthritis.
In this seminar we will discuss our latest work on the molecular mechanisms that control inflammasome activation in macrophages, especially the contribution of posttranslational modifications to this process.
