OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Although randomisation ensures the elimination of selection bias the ‘standard’ two armed trial is not without its difficulties. Many participants have a treatment preference, which can introduce post-randomisation bias. Attrition is a problem in most trials with 20% or more attrition not being uncommon. Similarly trials can be slow and expensive.
A TWICs design can potentially address some of these problems. Essentially a TWIC is a RCT that is embedded within a larger cohort. Elements of the design can mean that attrition is lower, participant preferences are dealt with, costs are lowered due to the use of unequal allocation and existing cohorts. In this talk I will discuss the basic elements of the design and the experience of the York Trials Unit in its use.
