OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
In this talk I will discuss how inflammation and end-stage (senescent) T cells collaborate to induce immunopathology in the skin, using human cutaneous leishmaniasis as a model. The interactions involved are likely to translate to many other clinical situatioins where senescent T cells and infammatioin co-exist in tissue envirionments. This raises the question of how best to tackle the problem and to reduce tissue damage. Should the T cells themselves, or the inflamed microenviroenviromnent, or both be the focus of drug targets.