Droplet microfluidics: a tool for massively parallel single-cell analysis, sorting and sequencing

Linas Mazutis works on technology development for single cell analysis. His work includes droplet microfludic systems, which they are using for applications including: single-cell transcriptomics, screening of single-cells producing therapeutic antibodies and integrated microfluidic platforms for long-term cell cultivation, monitoring and analysis. Droplet microfluidic systems have proven to be valuable tools for single-cell analysis, complex enzymatic assays, disease diagnostics, drug screening or directed evolution experiments. Due to reduced reaction volumes, unique liquid handling capabilities and increased analytical sensitivity microfluidic systems bring a new standard in high-throughput screens.