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On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
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Formation of common frameworks of cortical neural circuits based on the molecular bases of neuronal migration and collateral formation
We explore the structural mechanisms of brain function, with a focus on neuronal migration during cerebral cortex development and the role of the cytoskeleton. It highlights periventricular nodular heterotopia—a genetic disorder caused by mutations in filamin A—and introduces FILIP (filamin A interacting protein, FILIP1 for human), a molecule that degrades filamin A. Mutations in FILIP1 are linked to a spectrum of congenital disorders collectively termed FILIP1 disease. The study also presents new methods for visualizing neural circuits at the single-cell level, revealing early axonal targeting patterns that may inform future strategies for repairing disrupted neural networks. Unpublished findings and ongoing investigations into cytoskeletal regulation and neuropsychiatric implications are included.
Date:
4 December 2025, 11:00
Venue:
Sherrington Building, off Parks Road OX1 3PT
Venue Details:
Florence Buchanan Lecture Theatre
Speaker:
Professor Makoto Sato (The University of Osaka)
Organising department:
Department of Physiology, Anatomy and Genetics (DPAG)
Host:
Professor Zoltan Molnar (DPAG, University of Oxford)
Part of:
Neuroscience Theme Guest Speakers (DPAG)
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Hannah Simm
