The odds of a decision
Our decisions are often based on a combination of diverse factors such as sensory inputs, past actions, and estimates of value. There is increasing evidence that the brain does this via a simple operation: give each factor a weight, sum the results, use the sum to set the log odds of a coin, and flip the coin. This operation is called logistic classification. It is common in machine learning and economics, and has close cousins in psychology. I will illustrate this computation in multiple species, and will describe it in more detail in mice that perform an audiovisual decision task. Through large-scale recordings and localized inactivations, I will show how the log odds of a choice are progressively computed at key stages in visual cortex, auditory cortex, prefrontal cortex, and superior colliculus. The results point to a single view of how the brain makes a variety of decisions. It is optimal in certain conditions, but the brain uses it as a heuristic in a broader set of situations, by simply adjusting the weights as needed.
Date: 26 February 2025, 16:00
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Blakemore Lecture Theatre
Speaker: Professor Matteo Carandini (University College London)
Organising department: MRC Brain Network Dynamics Unit
Organiser: Sasha Tinelli (University of Oxford)
Organiser contact email address: sasha.tinelli@chch.ox.ac.uk
Host: Sasha Tinelli (University of Oxford)
Booking required?: Not required
Audience: Public
Editor: Sasha Tinelli