Influence of p53 on human immune and inflammatory responses in cancer and primary cells
Dr. Resnick’s work focuses on mechanisms of genome stability and on the function of the p53 regulatory network that signals stress and DNA chromosomal damage, using both yeast and human cells. Dr. Resnick’s Chromosome Stability Group has established new roles for p53 in immunity and inflammation, finding unique p53-NFkappaB interactions in human macrophages and showing that the innate immunity Toll-like receptor (TLR) gene family in primary human cells and many cancer lines responds to chromosome stressors, mostly via p53.
Date:
20 August 2015, 14:00 (Thursday, 17th week, Trinity 2015)
Venue:
NDM Building, Headington OX3 7FZ
Venue Details:
Basement Seminar Room
Speaker:
Dr Michael Resnick (NIH)
Organising department:
Ludwig Institute for Cancer Research, Oxford Branch
Organisers:
Mary Muers (Oxford Ludwig Institute, NDM Experimental Medicine),
Alexandra Ward (University of Oxford, Oxford Ludwig Institute, NDM Experimental Medicine)
Organiser contact email address:
alexandra.ward@ludwig.ox.ac.uk
Host:
Prof Xin Lu (Ludwig Cancer Research, Oxford Branch)
Part of:
Ludwig Institute Seminar Series
Topics:
Booking required?:
Not required
Audience:
Members of the University only
Editors:
Anne Bowtell,
Mary Muers
