During Michaelmas Term, OxTalks will be moving to a new platform (full details are available on the Staff Gateway).
For now, continue using the current page and event submission process (freeze period dates to be advised).
If you have any questions, please contact halo@digital.ox.ac.uk
The Cao Lab at BIOPIC, Peking University, and Changping Laboratory investigates humoral immunity and antibodies at single-cell and molecular levels, including:
Antibody response, immune escape, and immune imprinting in infectious diseases, including SARS-CoV-2
Development of antibody therapeutics and vaccines
Deciphering the relationship between targeting epitopes and functions of antibodies for various antigens
Computational and machine learning methods for modeling antibody-antigen interaction
A.Yisimayi et al.,Y. Cao, Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting. Nature (2023).
Y. Cao et al., Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution. Nature 614: 21-529. (2023).
Y. Cao et al., BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature 608: 593-602. (2022).
Y. Cao et al., Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies. Nature. 602: 657-663. (2022).
Y. Cao, et al., Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells. Cell. 182, 73-84.e16 (2020).
