Through careful strategic planning, coordination, investment, and oversight, we have developed a model for managing core facilities that addresses researchers’ needs within 3 schools across 2 campuses. Our management model is a partnership between core directors and central administrators that maintains operational control of each facility at the local level to ensure that the needs of researchers are being addressed. Central administrative oversight ensures that facilities are compliant with federal regulations, are financially sound, and align with institutional priorities. This hybrid management model is comprised of 4 pillars that are essential and necessary to ensure the long-term viability and success of facilities: core personnel, core space, institutional investment, and institutional evaluation.