OxTalks is Changing
OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
CRISPR-Cas9: Biological Roles, Mechanisms, And Evolution
The RNA-programmable CRISPR-Cas9 system has recently emerged as a transformative technology for rapid and efficient targeted genome editing, chromosomal marking and gene regulation. In this system, the endonuclease Cas9 or catalytically inactive Cas9 variants are programmed with single guide RNAs to target site-specifically any DNA sequence of interest. The system is efficient, versatile and easily programmable. DNA targeting by CRISPR-Cas9 has been quickly and broadly adopted by the scientific community to edit and silence genomes in a large variety of cells and organisms, including human cells, plants and mice. I will discuss the biological roles of CRISPR-Cas9, the mechanisms involved, the evolution of type II CRISPR-Cas components in bacteria and the applications of CRISPR-Cas9 as a novel genome engineering technology.
Date:
7 March 2016, 12:00
Venue:
Sherrington Building, off Parks Road OX1 3PT
Venue Details:
Large Lecture Theatre
Speaker:
Emmanuelle Charpentier (Max Planck Institute of Infection Biology, Berlin)
Organising department:
Centre for Neural Circuits and Behaviour
Organiser:
Fiona Woods (University of Oxford, Department of Physiology Anatomy and Genetics, Centre for Neural Circuits and Behaviour)
Organiser contact email address:
fiona.woods@cncb.ox.ac.uk
Host:
Professor Gero Miesenboeck (University of Oxford)
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Fiona Woods
