Dr Sarah De Val : ‘Transcriptional pathways controlling blood vessel development and differentiation’
The aim of our research group is to understand how signals are converted into gene expression in the vasculature through the study of transcriptional regulation during both developmental and disease angiogenesis. Although often considered a homogenous entity, endothelial cells are extremely heterogeneous, varying in origin, developmental stage, between and within vessels from different parts of the vascular tree and in different organs, and at different states of proliferation and quiescence. Our approach focuses on the identification, characterisation and very detailed dissection of vascular enhancers that direct expression within different sub-groups of the vasculature, combined with a study of the roles of both known and novel transcription factors in providing the activating and repressive signals necessary to pattern this complex vascular network.
Date: 22 May 2015, 13:00 (Friday, 4th week, Trinity 2015)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Large Lecture Theatre, ground floor
Speaker: Dr Sarah De Val (LICR, University of Oxford)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Sarah Noujaim (University of Oxford, Department of Physiology Anatomy and Genetics)
Organiser contact email address: sarah.noujaim@dpag.ox.ac.uk
Host: Professor Paul Riley (DPAG, University of Oxford)
Part of: DPAG Head of Department Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Sarah Noujaim